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When intake explains the result and the patient is well, with no concerning clinical or laboratory findings,it can often be attributed as the likely cause without an extensive search for disease

Sikiric 2020 lays this out in detail

AOD-9604 Dosing Protocols Based on Clinical Research Dosing recommendations for AOD-9604 are based on extensive human research including six clinical trials that evaluated various administration routes, doses, and treatment durations

This is a formidable problem for researchers

Its whitening effects are permanent only if you will maintain it (by avoiding exposure to sunlight)

What about Henderson or Summerlin do the same FDA rules apply